| 王林哲,胡敬芳,杨洋春,宋钰,李延生,高国伟.纸基微流控芯片及其水环境检测方法研究进展[J].中国造纸学报,2023,38(3):133-143 |
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| 纸基微流控芯片及其水环境检测方法研究进展 |
| Paper-based Microfluidic Chip and Its Research Progress in Water Environment Detection |
| 投稿时间：2023-04-07 |
| DOI：10.11981/j.issn.1000-6842.2023.03.133 |
| 中文关键词: 纸基微流控芯片 水环境污染 快速检测 |
| Key Words:paper-based microfluidic chip water environmental pollution rapid detection method |
| 基金项目:国家自然科学基金资助项目（61901042，62101053，62071054）；传感技术联合国家重点实验室开放课题（SKT1902）；北京市教育委员会科学研究计划资助项目（KM202211232004）。 |
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| 中文摘要: |
| 我国水环境污染问题较为突出，发展水环境污染物快速检测方法，是目前及时有效治理水环境问题的迫切需要。近年来，纸基微流控芯片（Paper-based microfluidic analytical devices，μPAD）在环境监测领域得到快速发展，它具有成本低、制作简单、试剂消耗少、携带方便、环保等特点，符合世界卫生组织（WHO）制定的现场快速检测装置“ASSURED”标准。本文综述了μPAD及其水环境检测方法的研究进展，首先介绍了在提升纸基材料性能方面取得的研究成果，讨论了μPAD的制备方法及其改进方案，并总结了几种应用于μPAD流体运动控制技术，然后重点介绍了基于μPAD的水环境快速检测方法与传感器构建方法取得的研究进展，最后讨论了μPAD目前的局限性并展望了其发展前景。 |
| Abstract: |
| Water environmental pollution is a serious problem in China. There is an urgent need to develop rapid detection methods for environmental pollutants in water. In recent years， paper-based microfluidic analytical devices （μPAD） have been rapidly developed in the field of environmental monitoring. It has advantages such as low cost， simple production， less reagent consumption and ease of carrying. It satisfied the standard of rapid on-site testing device “ASSURED” established by the World Health Organization （WHO）. Hence， in this paper， the research progress of μPAD in water environment detection is reviewed from following aspects. First， the paper-based materials improvement strategies for μPAD preparation are introduced， the μPAD preparation methods and strategies are discussed for enhancement of μPAD sensing performance， and the available applied methods of fluid motion control on μPAD are summarized. Then， the research progress of water environment rapid detection methods and corresponding sensor development principles based on μPAD are mainly introduced. Finally， the current limitations of μPAD are evaluated and the further research orientation of μPAD are prospected. |
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