张旭,杨桂花,蒋启蒙,薛玉,王月莹,徐义帆,陈嘉川.负载金属/金属氧化物纳米粒子纤维素基复合抗菌材料的制备及其研究进展[J].中国造纸学报,2024,39(4):49-60 本文二维码信息
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负载金属/金属氧化物纳米粒子纤维素基复合抗菌材料的制备及其研究进展
Research Progress in Preparation and Application of Cellulose-based Composite Antimicrobial Materials Loaded with Metal/Metal Oxide Nanoparticles
投稿时间:2023-09-27  修订日期:2023-10-12
DOI:10.11981/j.issn.1000-6842.2024.04.49
中文关键词:  纤维素  纳米粒子  金属/金属氧化物  负载  抗菌材料
Key Words:cellulose  nanoparticles  metal/metal oxide  load  antibacterial material
基金项目:山东省重点研发计划(2021CXGC010601);山东省自然基金项目(ZR202111260204)。
作者单位邮编
张旭 齐鲁工业大学(山东省科学院)山东济南250353 250353
杨桂花* 齐鲁工业大学(山东省科学院)山东济南250353 250353
蒋启蒙* 齐鲁工业大学(山东省科学院)山东济南250353 250353
薛玉 齐鲁工业大学(山东省科学院)山东济南250353 250353
王月莹 齐鲁工业大学(山东省科学院)山东济南250353 250353
徐义帆 潍坊潍森纤维新材料有限公司山东潍坊261000 261000
陈嘉川* 齐鲁工业大学(山东省科学院)山东济南250353 250353
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中文摘要:
      对人体健康产生危害的致病菌广泛存在于日常生活中,常用的化学杀菌剂在杀菌时会引起细菌的抗药性并污染环境。以金(Au)、银(Ag)、铜(Cu)及氧化锌(ZnO)等金属/金属氧化物纳米粒子(NPs)制备的无机抗菌剂,具备优异的物理抗菌效果,且不易引起细菌的抗药性和环境污染问题,已受到广泛关注。然而,金属/金属氧化物NPs存在易团聚和释放过快等问题,抗菌效果有限。本文综述了金属/金属氧化物NPs纤维素基复合抗菌材料的研究进展,并介绍了通过物理法、化学法和生物法制备Au、Ag、Cu及ZnO等NPs的技术方案,以及NPs的抗菌机理。以纤维素及其衍生物负载金属/金属氧化物NPs制备复合抗菌材料,不仅解决了NPs释放过快等问题,而且有助于提高NPs的抗菌稳定性,减轻环境污染。因此,负载金属/金属氧化物NPs纤维素基复合抗菌材料在生物医学、食品包装等领域具有广阔的应用前景。
Abstract:
      Pathogenic bacteria that cause harm to human health exist widely in daily life, and the chemical fungicides commonly used in sterilization will cause the resistance of bacteria and pollute the environment. Inorganic antibacterial agents prepared with metal/metal oxide nanoparticles (NPs) such as gold (Au), silver (Ag), copper (Cu) and zinc oxide (ZnO) have excellent physical antibacterial effects, and are not easy to cause bacterial resistance and environmental pollution problems, which have been widely concerned. However, metal/metal oxide NPs has some problems such as easy aggregation and fast release which limited its antibacterial effect. In this paper, the research progress of cellulose-based composite antimicrobial materials loaded with metal/metal oxide NPs were reviewed. The technical schemes for preparing NPs of Au, Ag, Cu and ZnO by physicochemical and biological methods, and the antibacterial mechanism of NPs were introduced. The preparation method of composite antibacterial material by loading metal/metal oxide NPs with cellulose and its derivatives not only solved the problem of fast release of NPs, but also contributed to improve the antimicrobial stability of NPs and reduced environmental pollution. Therefore, the cellulose-based composite antimicrobial materials loaded with metal/metal oxide NPs had broad application prospect in biomedicine, food packaging and other fields.
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