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Paper-based Microfluidic Chip and Its Research Progress in Water Environment Detection
Received:April 07, 2023  
DOI:10.11981/j.issn.1000-6842.2023.03.133
Key Words:paper-based microfluidic chip;water environmental pollution;rapid detection method
Fund Project:国家自然科学基金资助项目(61901042,62101053,62071054);传感技术联合国家重点实验室开放课题(SKT1902);北京市教育委员会科学研究计划资助项目(KM202211232004)。
Author NameAffiliationPostcode
WANG Linzhe* School of Automation, Beijing Information Science and Technology University, Beijing, 100192
Beijing Key Laboratory of Sensors, Beijing Information Science and Technology University, Beijing, 100101
Joint State Key Laboratory of Sensing Technology, Shanghai Institute of Microsystem and Information Technology, Shanghai, 200050 
200050
HU Jingfang School of Automation, Beijing Information Science and Technology University, Beijing, 100192
Beijing Key Laboratory of Sensors, Beijing Information Science and Technology University, Beijing, 100101
Key Laboratory of Modern Measurement and Control Technology, Ministry of Education, Beijing Information Science and Technology University, Beijing, 100192
Joint State Key Laboratory of Sensing Technology, Shanghai Institute of Microsystem and Information Technology, Shanghai, 200050 
200050
YANG Yangchun School of Automation, Beijing Information Science and Technology University, Beijing, 100192
Beijing Key Laboratory of Sensors, Beijing Information Science and Technology University, Beijing, 100101 
100101
SONG Yu School of Automation, Beijing Information Science and Technology University, Beijing, 100192
Beijing Key Laboratory of Sensors, Beijing Information Science and Technology University, Beijing, 100101
Joint State Key Laboratory of Sensing Technology, Shanghai Institute of Microsystem and Information Technology, Shanghai, 200050 
200050
LI Yansheng School of Automation, Beijing Information Science and Technology University, Beijing, 100192
Beijing Key Laboratory of Sensors, Beijing Information Science and Technology University, Beijing, 100101 
100101
GAO Guowei School of Automation, Beijing Information Science and Technology University, Beijing, 100192
Beijing Key Laboratory of Sensors, Beijing Information Science and Technology University, Beijing, 100101
Key Laboratory of Modern Measurement and Control Technology, Ministry of Education, Beijing Information Science and Technology University, Beijing, 100192
Joint State Key Laboratory of Sensing Technology, Shanghai Institute of Microsystem and Information Technology, Shanghai, 200050 
200050
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Abstract:
      Water environmental pollution is a serious problem in China. There is an urgent need to develop rapid detection methods for environmental pollutants in water. In recent years, paper-based microfluidic analytical devices (μPAD) have been rapidly developed in the field of environmental monitoring. It has advantages such as low cost, simple production, less reagent consumption and ease of carrying. It satisfied the standard of rapid on-site testing device “ASSURED” established by the World Health Organization (WHO). Hence, in this paper, the research progress of μPAD in water environment detection is reviewed from following aspects. First, the paper-based materials improvement strategies for μPAD preparation are introduced, the μPAD preparation methods and strategies are discussed for enhancement of μPAD sensing performance, and the available applied methods of fluid motion control on μPAD are summarized. Then, the research progress of water environment rapid detection methods and corresponding sensor development principles based on μPAD are mainly introduced. Finally, the current limitations of μPAD are evaluated and the further research orientation of μPAD are prospected.
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