纸基现场快速检测材料的应用研究进展

张雪; 肖贵华; 江骁雅; 陈雪梅; 李丽君; 杨光照; 高杰; 杜秀; 杜凡

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Research Progress on Application of Paper-based Point-of-care Testing Materials

Received:March 25, 2026 Revised:April 22, 2026

DOI：10.11981/j.issn.1000-6842.2026.03.140

Key Words:paper-based materials;point-of-care testing;selectivity;identification;high sensitivity

Fund Project:

国家特殊海外高层次人才计划项目

制浆造纸国家工程实验室基金

ZZY2025JBGS04

国家自然科学基金

32001276

国家特殊海外高层次人才计划项目；制浆造纸国家工程实验室基金（ZZY2025JBGS04）；国家自然科学基金（32001276）。

Author Name	Affiliation	Postcode
Zhang Xue^*	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Xiao Guihua	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 2Zhongqing Special Fiber Materials Co.， Ltd.， Langfang， Hebei Province， 065001 3Hebei Advanced Paper-based Functional Materials Technology Innovation Center， Langfang， Hebei Province， 065001 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Jiang Xiaoya	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 2Zhongqing Special Fiber Materials Co.， Ltd.， Langfang， Hebei Province， 065001 3Hebei Advanced Paper-based Functional Materials Technology Innovation Center， Langfang， Hebei Province， 065001 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Chen Xuemei	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Li Lijun	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Yang Guangzhao	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Gao Jie	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102
Du Xiu^*	2Zhongqing Special Fiber Materials Co.， Ltd.， Langfang， Hebei Province， 065001 3Hebei Advanced Paper-based Functional Materials Technology Innovation Center， Langfang， Hebei Province， 065001	065001
Du Fan^*	1China National Pulp and Paper Research Institute Co.， Ltd.， Beijing， 100102 4National Engineering Lab for Pulp and Paper， Beijing， 100102	100102

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Abstract:

Point-of-care Testing （POCT） technology integrates modern analytical chemistry with biosensing technology， enabling on-site testing and analysis of samples and rapid delivery of test results， which is a new type of analytical testing technology. Owing to the distinct merits of low cost， eco-friendliness， outstanding biocompatibility and excellent processability， paper-based materials have been recognized as an ideal substrate for POCT platforms. In this paper， a classification system for paper-based POCT materials was systematically outlined， covering multiple dimensions such as sensor principle design， substrate preparation processes， selection of substrates and functional materials， and the development of detection systems. The latest research advances in paper-based POCT materials for food safety testing， environmental pollutant monitoring， clinical testing， and public safety screening were summarized. Moreover， the critical technical bottlenecks and practical challenges encountered in the research and industrial translation of existing paper-based POCT materials were deeply discussed. The future core research directions and development trends in this field were envisioned， including the structural regulation of paper-based POCT materials and the construction of industrial production lines.

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